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Michael Menzel
Enhort
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79da26e1
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79da26e1
authored
Jan 17, 2019
by
Michael Menzel
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# Enhort: Genomic Position Profiling
The rise of high-throughput methods in genomic research greatly expanded our
knowledge about the functionality of the genome. At the same time, the amount
of available genomic position data increased massively, e.g., through genome-wide
profiling of protein binding, virus integration or DNA methylation.
However, there is no specialized software to investigate integration site profiles
of virus integration or transcription factor binding sites by correlating the sites
with the diversity of available genomic annotations.
Here we present Enhort, a user-friendly software tool for relating large sets of
genomic positions to a variety of annotations. It functions as a statistics based
genome browser, not focused on a single locus but analyzing many genomic positions
simultaneously. Enhort provides comprehensive yet easy-to-use methods for statistical
analysis, visualization, and the adjustment of background models according to
experimental conditions and scientific questions.
# Availability
Enhort is publicly available online at www.enhort.mni.thm.de and published under GNU General Public License.
# Build
A seperate SETUPINSTR.md file is available containing instructions to run Enhort on your own infrastructure.
# VM
There is a VirtualBox image with Enhort set up for reference and to test with your own data:
https://homepages.thm.de/~mmnz21/enhort_vm_jan_2019.tar.gz
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