Accessibility with VoiceOver (macOS)
The Screenreader VoiceOver reads the possible answers as follows: 1st element: The number of the answer, for example a 2nd: The text of the answer. 3rd: The buttons to select the answers. These buttons are named with the number of the answer. Just the last described element is clickable with a screen reader. This slows down the process of selecting an answer. A user with a screen reader could select his or her answer faster if for example the element with the text of the answer would be clickable. Another possibility would be to combine this three elements in one, so a screen reader would read it as follows:
a: Text of the answer.
This would be the best answer because this solutions would have the least number of elements to scroll through with a screen reader.